Plasmid DNA Manufacturing Market, Revenue Growth, Key Factors, Major Companies, Forecast To 2028

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The Viral Vector and Plasmid DNA manufacturing market is estimated to reach USD 4.70 billion by 2028 from USD 686.69 million in 2020, delivering a CAGR of 23.8% through the forecast period.

According to the current analysis of Reports and Data, the global Plasmid DNA Manufacturing Market is expected to reach USD 4.70 billion by the year 2028, with a CAGR of 23.8% during the forecast period. Viral and non-viral vectors have emerged as an efficient delivery mechanism for the development of innovative medicines. Viral vectors and plasmid DNA are products of gene therapy, which are used for the treatment of a large number of diseases such as cancer and other chronic disorders. The advantages of gene vaccines and gene therapy over conventional vaccines and therapies include the ability to induce a wide range of immune response types. The major driving factors that are boosting the growth of Plasmid DNA Manufacturing market are the global rise in the incidence of cancer, increase in geriatric population susceptible to diseases, government initiatives grants and the increase in investment by private companies on RD activities of viral vectors and plasmid DNA manufacturing.

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Key findings from the report suggest

  • Increasing acceptance of viral vector-based advanced treatments is likely to drive the segment in Plasmid DNA Manufacturing market. The significant share is due to the use of adeno associated virus, lentivirus, and others.
  • By application, cancer is expected to account for the largest share of the market, followed by genetic disorder segment, which occupied a market share of around 33.3% in 2017.
  • The following are the significant genetically modified therapies rigorously studied and analyzed, namely, LUXTURNA, YESCARTA, Kymriah, INVOSSA, Zalmoxis, Strimvelis, Imlygic, Neovasculagen, Rexin-G, Oncorine, and Gendicine. Amongst these, YESCARTA and Kymriah are T-cell based gene therapies that were recently approved by the FDA, in October 2017 and August 2017, respectively. Besides, over 430 gene therapy candidates are presently in different stages of clinical development, for which over 500 clinical studies are currently underway in various regions across the globe.
  • The growing number of gene therapy candidates, coupled with their rapid progression through multiple phases of clinical development, is expected to continue to create an increasing demand for vectors.
  • North America dominates the global Plasmid DNA Manufacturing market due to a large patient pool, and high acceptance of advanced treatments in the region. The region is estimated to maintain its dominance during the forecast period. Moreover, rising healthcare expenditure, availability of approved gene therapy treatments, and increasing investments are key factors that are anticipated to boost the Plasmid DNA Manufacturing market in the next few years.
  • The Plasmid DNA Manufacturing market in the Asia Pacific is projected to expand at a notable CAGR due to increasing awareness regarding viral vector-based products in developing countries and rising research initiatives in countries such as Japan and China.

Competitive Outlook of the Global Plasmid DNA Manufacturing Market

The globla Plasmid DNA Manufacturing market study focuses on the revenue growth trajectories of the leading companies in this market. This section of the report throws light on the highly competitive landscape of the Plasmid DNA Manufacturing market, pointing out the major players. The report further discusses the strategic initiatives undertaken by each of these market players, including mergers acquisitions, collaborations, joint ventures, new product launches, new business deals, and technological innovations.

Top Companies Profiled in the Report:

FUJIFILM Diosynth Biotechnologies, Kaneka Eurogentec S.A, Fin vector, Spark therapeutics, Cobra biologics, Cell and gene therapy catapult, Renova Therapeutics, Shenzhen SiBiono GeneTech Co., Ltd, Thermo Fisher Scientific, Inc, 4D Molecular Therapeutics.

Plasmid DNA Manufacturing Market Segmentation:

By Product (Revenue, USD Million; 2018-2028)

  • Plasmid DNA
  • Viral Vectors
  • Non-viral Vectors

By Workflow (Revenue, USD Million, 2018 - 2028)

  • Upstream Processing
    • Vector Amplification Expansion
    • Vector Recovery/Harvesting
  • Downstream Processing
    • Purification
    • Fill-finish

By Disease (Revenue, USD Million; 2018-2028)

  • Cancer
  • Inherited Disorders
  • Viral Infections
  • Others

By Application (Revenue, USD Million, 2018-2028)

  • Antisense, RNAi, Molecular Therapy
  • Vaccinology

By Sales channel (Revenue, USD Million; 2018-2028)

  • Channel sales
  • Direct Sales

By End user: (Revenue, USD Million; 2018-2028)

  • Pharmaceutical and Biopharmaceutical Companies
  • Research Institutes

Geographic Segment Covered in the Report:

The Plasmid DNA Manufacturing report provides information about the market area, which is further subdivided into sub-regions and countries/regions. In addition to the market share in each country and sub-region, this chapter of this report also contains information on profit opportunities. This chapter of the report mentions the market share and growth rate of each region, country, and sub-region during the estimated period.

  • North America (USA and Canada)

  • Europe (UK, Germany, France and the rest of Europe)

  • Asia Pacific (China, Japan, India, and the rest of the Asia Pacific region)

  • Latin America (Brazil, Mexico, and the rest of Latin America)

  • Middle East and Africa (GCC and rest of the Middle East and Africa)

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